Rat Jagged 1 quantitates rat Jagged 1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat Jagged 1.The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
|Research Use Only|
|Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers|
|4 hr 45 min|
|Serum, Plasma, Supernatant|
|2°C to 8°C|
|1 hr 20 min|
|Supernatant, 50 µL; Plasma, 50 µL; Serum, 50 µL|
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