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Invitrogen™ Rat MMP-2 ELISA Kit Non-distribution product as customer accommodation.

Rat MMP-2 quantitates rat MMP-2 in serum, plasma, supernatant.

$491.00 - $2205.00

Specifications

Regulatory Status Research Use Only
Storage Requirements 2°C to 8°C
Target MMP2
Product Type ELISA
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
ERA42RBX5 Non-distribution product as customer accommodation.
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Invitrogen™
ERA42RBX5
5 x 96 Tests
Each for $2,205.00
Add to cart
 
ERA42RB Non-distribution product as customer accommodation.
View Documents
Invitrogen™
ERA42RB
96 Tests
Each for $491.00
Add to cart
 
Description

Description

Rat MMP-2 quantitates rat MMP-2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat MMP-2.

MMP (matrix metalloproteinase) are proteolytic enzymes capable of degrading connective tissue components. MMP have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPa and TIMPs play a significant role in regulating angiogenesis. MMP2 is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids, and contains the basic structure of propeptide, catalytic, and hemopexin domains. The matrix metalloproteinases (MMPs) are a family of at least eighteen secreted and membrane-bound zincendopeptidases. Collectively, these enzymes can degrade all the components of the extracellular matrix, including fibrillar and non-fibrillar collagens, fibronectin, laminin and basement membrane glycoproteins. In general, a signal peptide, a propeptide, and a catalytic domain containing the highly conserved zinc-binding site characterizes the structure of the MMPs. Functionally, MMP2 is involved in tissue remodeling. Mutations in MMP-2 gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms of MMP-2 have been found.
Specifications

Specifications

Research Use Only
MMP2
Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
4 hr 45 min
Serum, Plasma, Supernatant
2°C to 8°C
ELISA
0.6 ng/mL
1 hr 20 min
Supernatant, 50 µL; Plasma, 50 µL; Serum, 50 µL
SDS
Product Certifications
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