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Invitrogen™ Rat SCF ELISA Kit

Rat SCF quantitates rat SCF in serum, plasma, supernatant.

Manufacturer:  Invitrogen™ ERA53RBX5


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Catalog No. ERA53RBX5

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Rat SCF quantitates rat SCF in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat SCF.

Stem cell factor (SCF) is the ligand of the c-Kit oncogene and is expressed by various structural and inflammatory cells in the airways. Binding of SCF by the c-Kit receptor leads to homodimerization of the receptor and the activation of signalling pathways such as PI-3, PLC-gamma, Jak/STAT, and MAP kinase pathways. SCF expression leads to the induction of mast cell survival and the expression and release of histamine, pro-inflammatory cytokines and chemokines. The inhibition of the SCF/c-Kit pathway leads to a decrease in histamine levels, mast cell and eosinophil infiltration, IL-4 production and airway hyperresponsiveness, suggesting this pathway may be a useful therapeutic target in inflammatory diseases such as asthma. At least two isoforms of SCF are known to exist.


710-712; blz; c-Kit ligand; Clo; cloud gray; Con; contrasted; CSF; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; Gb; grizzle-belly; hematopoietic growth factor KL; H-SCF; Kit ligand; Kitl; Kitlg; kit-ligand; KL-1; mast cell growth factor; Mgf; M-SCF; Processed kit ligand; SCF; SF; SHEP7; sKITLG; Sl; SLF; Soluble KIT ligand; Steel factor; steel factor/kit ligand; stem cell factor; stem cell factor KL-1; stem cell factor, CSF
Research Use Only
2°C to 8°C
4 hr 45 min
5 x 96 Tests
12 pg/mL
Colorimetric Microplate Reader
12 to 3,000 pg/mL
Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Supernatant, 50 µL; Plasma, 50 µL; Serum, 50 µL
1 hr 20 min
Serum, Plasma, Supernatant
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