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Invitrogen™ Rat TNF-alpha ELISA (For Lysates) Kit Non-distribution product as customer accommodation.

Rat TNF-alpha quantitates rat TNF-alpha in cell lysate, tissue homogenate.

$491.00 - $2205.00

Specifications

Regulatory Status Research Use Only
Storage Requirements 2°C to 8°C
Target TNF alpha
Product Type ELISA
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
ERA57RBX5 Non-distribution product as customer accommodation.
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Invitrogen™
ERA57RBX5
5 x 96 Tests
Each for $2,205.00
Add to cart
 
ERA57RB Non-distribution product as customer accommodation.
View Documents
Invitrogen™
ERA57RB
96 Tests
Each for $491.00
Add to cart
 
Description

Description

Rat TNF-alpha quantitates rat TNF-alpha in cell lysate, tissue homogenate. The assay will exclusively recognize both natural and recombinant rat TNF-alpha.

TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions. Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice. Other functions of TNF-alpha include its role in the immune response to bacterial, viral, parasitic and certain fungal infections, as well as its role in the necrosis of specific tumors. TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon-gamma in its cytotoxicity. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.
Specifications

Specifications

Research Use Only
TNF alpha
Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
4 hr 45 min
Cell Lysates, Tissue Homogenates
2°C to 8°C
ELISA
25 pg/mL
1 hr 20 min
Cell Lysate, 50 µL; Tissue Homogenate, 50 µL
SDS
Product Certifications
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