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Rat VEGF (aa 27-190), Recombinant Protein, Invitrogen™ Non-distribution product as customer accommodation.

HEK293 cells Recombinant Protein

$244.00 - $2560.00

Specifications

Recombinant Yes
Name Rat VEGF (aa 27-190)
For Use With (Application) Control, ELISA, Western Blot
Concentration 200 µg/mL
Conjugate Unlabeled
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Products 4
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
PIRP87940 Non-distribution product as customer accommodation.
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Thermo Scientific
RP87940
10 µg
Each for $244.00
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PIRP87941 Non-distribution product as customer accommodation.
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Thermo Scientific
RP87941
25 µg
Each for $449.50
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PIRP87942 Non-distribution product as customer accommodation.
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Thermo Scientific
RP87942
100 µg
Each for $963.00
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PIRP87943 Non-distribution product as customer accommodation.
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Thermo Scientific
RP87943
500 µg
Each for $2,560.00
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Description

Description

VEGF (vascular endothelial growth factor) which is a 45 kDa homodimeric, disulfide-linked glycoprotein involved in angiogenesis which promotes tumor progression and metastasis. VEGF has a variety of effects on vascular endothelium, including the ability to promote endothelial cell viability, mitogenesis, chemotaxis, and vascular permeability. The VEGF family currently includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF. VEGF and its receptor system have been shown to be the fundamental regulators in the cell signaling of angiogenesis. Most tumors have the absolute requirement of angiogenesis, and VEGF has been described as the most potent angiogenic cytokine linked to this process. To date 5 different isoforms of VEGF have been described. These isoforms are generated as the result of alternative splicing from a single VEGF gene. These various isoforms have been shown to bind to two tyrosine-kinase receptors flt-1 (VEGFR-1) and flk-1/KDR (VEGFR-2), which have been found to be expressed almost exclusively on endothelial cells. VEGF and its high-affinity binding receptors, the tyrosine kinases FLK1 and FLT1, are thought to be important for the development of embryonic vasculature. Studies have shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which binds vascular endothelial growth factor with high affinity, playing an inhibitory role in angiogenesis. Elevated levels of VEGF is linked to POEMS syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal gammopathy, Skin changes) also known as Crow-Fukase syndrome which affects multiple organs in the body.
Specifications

Specifications

Yes
Control, ELISA, Western Blot
Unlabeled
5 mM citric acid, 5 mM sodium phosphate with 150 mM NaCl and no preservative; pH 4
HEK293 cells
-20°C
P16612
VEGFA
>95%
Rat VEGF (aa 27-190)
200 µg/mL
Liquid
angiogenic factor; etID309976.16; eVEGF120; eVEGF164; human VEGF121 homolog; MGC70609; MVCD1; ovine vascular endothelial growth factor; RP1-261G23.1; unnamed protein product; VAS; vascular endothelial growth factor; vascular endothelial growth factor (VEGF) precursor; vascular endothelial growth factor 121 isoform; vascular endothelial growth factor 164; vascular endothelial growth factor 165 b; vascular endothelial growth factor 182 isoform; vascular endothelial growth factor 188; vascular endothelial growth factor 188 isoform; vascular endothelial growth factor 189; vascular endothelial growth factor A; vascular endothelial growth factor A121; vascular endothelial growth factor A165; vascular endothelial growth factor Aa; Vascular endothelial growth factor A-A; vascular endothelial growth factor isoform 165; Vascular permeability factor; Vasculotropin; vegf; VEGF1; VEGF164; VEGF182; VEGF188; VEGFA; vegf-a; vegfaa; VEGF-A-A; VEGFMGC70609; VPF; VPF ant; wu:fj82c06
RUO
Rat
83785
19.2 kD
SDS
Product Certifications
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