RbAp46 Mouse anti-Human, Clone: OTI4C9, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525735
DescriptionRetinoblastoma protein (Rb) associated protein 46 (RbAp46) is a nuclear protein that has been shown to interact directly with retinoblastoma protein and is a component of the mSin3 corepressor complex as are the histone deacetylase proteins (HDACs). RbAp46 shares about 75% sequence identity with the closely related RbAp48, and appears to be functionally related to the yeast MSI1 protein in that overexpression of RbAp46 suppresses heat shock sensitivity in a RAS pathway dependent manner. RbAp46 has also been demonstrated to be up-regulated by the Wilms ft. tumor suppressor gene product, WT1. Additionally, cells transfected with RbAp46 have shown strong inhibition of growth.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|RbAp46, G1/S transition control protein-binding protein RbAp46, RBBP-7, histone acetyltransferase type B subunit 2, histone-binding protein RBBP7, nucleosome-remodeling factor subunit RBAP46, retinoblastoma-binding protein 7, retinoblastoma-binding protein RbAp46, retin|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of RBBP7 produced in HEK293T cell|
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