RBPJ Mouse anti-Human, Clone: OTI4B11, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527166
DescriptionTranscriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|CBF1, IGKJRB, IGKJRB1, KBF2, RBP-J, RBPJK, RBPSUH, SUH, csl, CBF-1, H-2K binding factor-2, RBP-J kappa, RBP-JK, immunoglobulin kappa J region recombination signal binding protein 1, recombining binding protein suppressor of hairless, renal carcinoma antigen NY-REN-30, suppressor of hairless homolog|
|-20° C, Avoid Freeze/Thaw Cycles|
|Human recombit protein fragment corresponding to amino acids 1-243 of RBPJ produced in E.coli|
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