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RCC1 Rabbit anti-Human, Mouse, Non-human primate, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Supplier: Proteintech Group Inc 221421AP150UL
Description
This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human RCC1.
TDP43 was first identified as a novel cellular protein that binds to HIV-1 virus TAR DNA sequence motifs and acts a transcriptional repressor to the HIV-1 LTR. Later experiments revealed that TDP43 also regulates the splicing of exon 9 of the cystic fibrosis transmembrane conductance regular (CFTR), most likely through the association with the UG repeats at the 3"e; splice site. A hyperphosphorylated, ubiquitinated, and cleaved form of TDP43 known as pathologic TDP43 is the major disease protein in ubiquitin-positive, tau-, and alpha-synuclein-negative frontotemporal dementia (FLTD-U). TDP43 is not related to TRBP1, and RNA binding protein that binds HIV-1 TAR RNA sequences.Specifications
RCC1 | |
Polyclonal | |
Unconjugated | |
RCC1 | |
Cell cycle regulatory protein, CHC1, RCC1, RCC1 I | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
100088, 1104, 682908 | |
-20°C | |
Liquid |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
0.38 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P18754, Q8VE37 | |
RCC1 | |
RCC1 Fusion Protein Ag17569 | |
150 μL | |
Primary | |
Human, Mouse, Non-human Primate, Rat | |
Antibody | |
IgG |
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