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RCC1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 223351AP

Catalog No. 50-173-3833


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Description

Description

This antibody is a rabbit polyclonal antibody raised against full length RCC1 of human origin.

TDP43 was first identified as a novel cellular protein that binds to HIV-1 virus TAR DNA sequence motifs and acts a transcriptional repressor to the HIV-1 LTR. Later experiments revealed that TDP43 also regulates the splicing of exon 9 of the cystic fibrosis transmembrane conductance regular (CFTR), most likely through the association with the UG repeats at the 3"e; splice site. A hyperphosphorylated, ubiquitinated, and cleaved form of TDP43 known as pathologic TDP43 is the major disease protein in ubiquitin-positive, tau-, and alpha-synuclein-negative frontotemporal dementia (FLTD-U). TDP43 is not related to TRBP1, and RNA binding protein that binds HIV-1 TAR RNA sequences.
Specifications

Specifications

RCC1
0.27 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P18754, Q8VE37
Cell cycle regulatory protein, CHC1, RCC1, RCC1 I
Rabbit
IgG
150 μL
-20°C
Primary
100088, 1104, 682908
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
RCC1
Liquid
Rcc1
RCC1 Fusion Protein Ag17809
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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