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R&D Systems™ Recombinant Rat PD-1 Fc Chimera Protein, CF

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Applications: Bioactivity

Manufacturer:  R&D Systems™ 9814PD100

Catalog No. 98-14P-D100


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Description

Description

Measured by its binding ability in a functional ELISA. When Recombinant Rat PD-L1/B7-H1 Fc Chimera (Catalog # 9835-B7 ) is coated at 1 μg/mL (100 μL/well), the concentration of Recombinant Rat PD-1 Fc Chimera (Catalog # 9814-PD) that produces 50% optimal binding response is typically 0.1-0.6 μg/mL.
Specifications

Specifications

NP_001100397
Lyophilized from a 0.2 µm filtered solution in Tris, NaCl and EDTA with Sucrose and Mannitol.
M.W. (Observed): 57-70 kDa, reducing conditions; M.W. (theoretical): 43 kDa
100 µg
12 months from date of receipt, <= -20 °C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, <= -20 °C under sterile conditions after reconstitution.
<0.10 EU / 1 µg of the protein by the LAL method.
PD-1
Rat
Reconstitute at 500 µg/mL aq. soln..
Bioactivity
Bioactivity
5133
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
Mouse myeloma cell line, NS0-derived rat PD-1 protein Rat PD-1 (Leu25-Gln167) (N-terminus) Accession # NP_001100397 IEGRMDP Mouse IgG2a (Glu98-Lys330) (C-terminus)
RUO
CD279, CD279 antigen, hPD-1, PD1, PD1hPD-l, PDCD1, programmed cell death 1, programmed cell death protein 1, Protein PD-1, SLEB2
Unconjugated
Yes
Lyophilized from a 0.2 μm filtered solution in Tris, NaCl and EDTA with Sucrose and Mannitol.
PD-1
SDS
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