REEP5 Mouse anti-Human, Clone: OTI4D2, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526063
DescriptionREEP5 (receptor expression-enhancing protein 5), also known as C5orf18, DP1, TB2 or D5S346, is a 189 amino acid multi-pass membrane protein. Thought to promote the functional cell surface expression of olfactory receptors, REEP5 belongs to the DP1 family and is encoded by a gene that maps to chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the parm of chromosome 5 leads to cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|REEP5, C5orf18, D5S346, Deleted in polyposis 1, Deleted in polyposis, Polyposis locus protein 1, Protein TB2, Receptor accessory protein 5, TB2, YOP1, DP1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of REEP5 produced in HEK293T cell|
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