Thermo Scientific™ NAC 100

Digest and decontaminate clinical specimens for isolation of acid-fast bacilli and fungi using NAC

Supplier:  Thermo Scientific™ R21079

Catalog No. R21079

Description

Digest and decontaminate clinical specimens for isolation of acid-fast bacilli and fungi with Thermo Scientific™ Remel™ NAC (50 and 100). Respiratory specimens such as sputum contain mucin which trap microorganisms. Such specimens require liquefaction to release the mycobacterial cells prior to inoculation of media¹. The N-acetyl-L-cysteine (NAC) method is the widely used procedure for digestion and decontamination of specimens for recovery of Mycobacterium spp². Reep and Kaplan demonstrated NAC can be used with sodium citrate as a diluent liquefies specimens for the recovery of fungi^3,4.

NAC serves as a mucolytic agent by disrupting disulfide bonds in the mucous of sputum, gastric lavage and other body fluids.

NAC 100 contains 0.50g of N-acetyl-L-cysteine (CAS 616-91-1) and NAC 50 contains 0.25g of N-acetyl-L-cysteine (CAS 616-91-1) which needs to be diluted with sodium citrate to form a solution that liquefies specimens for the recovery of fungi.

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Specifications

• Description: NAC 100
• Product Type: Bacterial and Fungal Isolation
• Packaging Type: 6 Vials/Pk.
• Quantity: 6 x 100 mL