RENT1, Polyclonal, Bethyl Laboratories
Goat Polyclonal Antibody
Manufacturer: Bethyl Laboratories, Inc A300036AM
The recommended shelf life for this product is 1 year from date of receipt.This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene.
|TBS with 0.1% BSA and 0.09% sodium azide|
|Regulator of nonsense transcripts 1; ATP-dependent helicase RENT1; Nonsense mRNA reducing factor 1; NORF1; Up-frameshift suppressor 1 homolog; hUpf1; RENT1; KIAA0221; UPF1;|
|Between 250 and 300|
|Antigen affinity chromatography|
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