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RET Mouse anti-Human, Clone: 188CT11.2.3, Abnova™

Mouse monoclonal antibody raised against human RET.

Manufacturer:  Abnova Corporation MAB12308

Catalog No. 89-934-853


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Description

Description

This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq]

Specifications

Specifications

RET
188CT11.2.3
Mouse monoclonal antibody raised against human RET.
In ascites (0.09% sodium azide)
CDHF12/HSCR1/MEN2A/MEN2B/MTC1/PTC/RET-ELE1/RET51
Mouse
IgM, kappa
RUO
Primary
5979
Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Unconjugated
Immunohistochemistry (1:50-1:100) Immunofluorescence (1:10-1:50) Western Blot (1:500-1:16000) The optimal working dilution should be determined by the end user.
Liquid
RET
Recombinant His fusion protein corresponding to human RET.
100 uL
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Monoclonal
Human
SDS
Documents
Product Certifications
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