RET Mouse anti-Human, Clone: 188CT11.2.3, Abnova™

Mouse monoclonal antibody raised against human RET.

Supplier:  Abnova Corporation MAB12308

Catalog No. 89-934-853

Description

This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq]

Specifications

• Antigen: RET
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (1:50-1:100) Immunofluorescence (1:10-1:50) Western Blot (1:500-1:16000) The optimal working dilution should be determined by the end user.
• Gene Alias: CDHF12/HSCR1/MEN2A/MEN2B/MTC1/PTC/RET-ELE1/RET51
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
• Clone: 188CT11.2.3
• Description: Mouse monoclonal antibody raised against human RET.
• Formulation: In ascites (0.09% sodium azide)
• Gene Symbols: RET
• Immunogen: Recombinant His fusion protein corresponding to human RET.
• Regulatory Status: RUO
• Gene ID (Entrez): 5979
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgM κ