Epredia™ Lab Vision™ Ret Oncoprotein Ab-1, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Epredia™ Ret Oncoprotein Ab-1, Mouse Monoclonal Antibody.

Supplier:  Epredia™ MS1120S

Catalog No. MS1120S

Description

The ret proto-oncogene encodes a cell surface glycoprotein belonging to a member of the receptor tyrosine kinase family and is located on chromosome 10q11.2. Three main 3' splice isoforms have been characterized from papillary thyroid carcinomas, themselves originating from thyroid epithelial cells. Ret expression is observed in several regions of the central nervous system; in the developing cranial nerve ganglia and a subset of cells within dorsal root ganglia, in motor neurons in the spinal cord and hindbrain, in neuroretina and the growing tips of the renal collecting ducts in developing kidney.

Host Species: Mouse

Clone: 3F8

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: C-terminal

Immunogen: Recombinant protein encoding the extreme C-terminal cytoplasmic region of the human ret oncoprotein

Positive Control: Enteric ganglion cells, Small intestine

Cellular Localization: Cytoplasmic

Recommended for:

• Immunohistochemistry (Formalin/paraffin only)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Ret Oncoprotein Ab-1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Immunogen: Recombinant protein encoding the extreme C-terminal cytoplasmic region of the human ret oncoprotein
• Quantity: 1 mL
• Research Discipline: Signal Transduction
• Target Species: Human
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin)
• Clone: 3F8
• Host Species: Mouse
• Purification Method: Enteric ganglion cells, small intestine
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated