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Epredia™ Lab Vision™ Ret Oncoprotein Ab-1, Mouse Monoclonal Antibody
Provide accurate, reproducible results with the Epredia™ Ret Oncoprotein Ab-1, Mouse Monoclonal Antibody.
Supplier: Epredia™ MS1120S
Description
The ret proto-oncogene encodes a cell surface glycoprotein belonging to a member of the receptor tyrosine kinase family and is located on chromosome 10q11.2. Three main 3' splice isoforms have been characterized from papillary thyroid carcinomas, themselves originating from thyroid epithelial cells. Ret expression is observed in several regions of the central nervous system; in the developing cranial nerve ganglia and a subset of cells within dorsal root ganglia, in motor neurons in the spinal cord and hindbrain, in neuroretina and the growing tips of the renal collecting ducts in developing kidney.Host Species: Mouse
Clone: 3F8
Isotype: IgG1
Species Reactivity: Human. Others not known.
Epitope: C-terminal
Immunogen: Recombinant protein encoding the extreme C-terminal cytoplasmic region of the human ret oncoprotein
Positive Control: Enteric ganglion cells, Small intestine
Cellular Localization: Cytoplasmic
Recommended for:
- Immunohistochemistry (Formalin/paraffin only)
Note:
USA: RUO; Int'l: RUO
Specifications
Ret Oncoprotein Ab-1 | |
Monoclonal | |
Unconjugated | |
Recombinant protein encoding the extreme C-terminal cytoplasmic region of the human ret oncoprotein | |
1 mL | |
Signal Transduction | |
Human | |
IgG1 |
Immunohistochemistry (Paraffin) | |
3F8 | |
Mouse | |
Enteric ganglion cells, small intestine | |
RUO | |
Primary | |
Concentrated |
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