Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Thermo Scientific™ Lab Vision™ Retinoblastoma (Rb) Ab-1, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ Retinoblastoma (Rb) Ab-1, Mouse Monoclonal Antibody.

$165.00 - $906.00

Specifications

Antigen Retinoblastoma (Rb) Ab-1
Clone 1F8; same as Rb1
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Host Species Murine
View More Specs

Products 10
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
MS107B
View Documents
Thermo Scientific™
MS107B
Biotinylated Ab with BSA and Azide 1mL
Each for $906.00
Add to cart
 
MS107B0
View Documents
Thermo Scientific™
MS107B0
Biotinylated Ab with BSA and Azide 100μL
Each for $267.50
Add to cart
 
MS107B1
View Documents
Thermo Scientific™
MS107B1
Biotinylated Ab with BSA and Azide 500μL
Each for $567.00
Add to cart
 
MS107P0
View Documents
Thermo Scientific™
MS107P0
Purified Ab with BSA and Azide 100μL
Each for $165.00
Add to cart
 
MS107P1
View Documents
Thermo Scientific™
MS107P1
Purified Ab with BSA and Azide 500μL
Each for $488.50
Add to cart
 
MS107P1ABX
View Documents
Thermo Scientific™
MS107P1ABX
Ab without BSA/Azide (Frozen) 100μL
Each for $496.00
Add to cart
 
MS107PABX
View Documents
Thermo Scientific™
MS107PABX
Ab without BSA/Azide (Frozen) 200μL
Each for $749.00
Add to cart
 
MS107R7
View Documents
Thermo Scientific™
MS107R7
Ready-to-use for IHC (UVLP) 7mL
Each for $297.00
Add to cart
 
MS107P
View Documents
Thermo Scientific™
MS107P
Purified Ab with BSA and Azide 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
View substitute products »
MS107R1
View Documents
Thermo Scientific™
MS107R1
Ready-to-use for IHC (UVLP) 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
View substitute products »
Description

Description

Provide accurate, reproducible results with the Thermo Scientific™ Retinoblastoma (Rb) Ab-1, Mouse Monoclonal Antibody.

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.

Host Species: Mouse

Clone: 1F8; same as Rb1

Isotype: IgG1

Species Reactivity: Human. Does not react with mouse and rat. Others not known.

Epitope: aa 703-722

Immunogen: Recombinant human Rb protein

Molecular Weight: 105kDa

Positive Control: Ls174T, HT29, HUVEC cells; Normal colon, Breast CA and colon CA

Cellular Localization: Nuclear Ab-1 specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It reacts with hyperphosphorylated and un (under) phosphorylated form of Rb protein. It shows no cross reaction with p107 and p130.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Retinoblastoma (Rb) Ab-1
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Murine
Cancer and Tumor Biology
Recombinant human Rb protein
1F8; same as Rb1
Monoclonal
RUO
Primary
IgG1
SDS
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit