Tocris RETRA hydrochloride
Antitumor agent; suppresses mutant p53-bearing cancer cells
Manufacturer: Tocris 3214/50
DescriptionAntitumor agent. Inhibits tumor cell growth in a mutant p53- and p73-dependent manner in vitro and in vivo (IC50 = 4µM). Transcriptionally activates expression of p53-responsive genes and induces activation of effector caspases 3 and 7.
- Chemical Name: 2-[(4,5-Dihydro-2-thiazolyl)thio]-1-(3,4-dihydroxyphenyl)ethanone hydrochloride
- Formula: C11N11NO3S2.HCl
- CAS Number: 1173023-52-3
- Solubility: Soluble to 100mM in DMSO
- Purity: >99
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