Tocris™ RETRA hydrochloride

Antitumor agent; suppresses mutant p53-bearing cancer cells

Manufacturer: Tocris™ 3214/50

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Catalog No. 32-145-0

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Disclaimers:

For Research Use Only


    Specifications

    Product Type RETRA hydrochloride
    Inhibitors RETRA hydrochloride
    Purity >99
    Molecular Weight 305.8
    Quantity 50mg

    Antitumor agent. Inhibits tumor cell growth in a mutant p53- and p73-dependent manner in vitro and in vivo (IC50 = 4µM). Transcriptionally activates expression of p53-responsive genes and induces activation of effector caspases 3 and 7.

    • Chemical Name: 2-[(4,5-Dihydro-2-thiazolyl)thio]-1-(3,4-dihydroxyphenyl)ethanone hydrochloride
    • Formula: C11N11NO3S2.HCl
    • CAS Number: 1173023-52-3
    • Solubility: Soluble to 100mM in DMSO
    • Purity: >99

  • Description & Specifications

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