RFXANK Mouse anti-Human, Clone: OTI3E7, liquid, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene TA504271
DescriptionMajor histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity.
|Full length human recombit protein of human RFXANK produced in HEK293T cell.|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide|
|ANKRA1, BLS, F14150_1, RFX-B|
|-20° C, Avoid Freeze/Thaw Cycles|
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