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RFXANK Mouse anti-Human, Clone: OTI3E7, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA504271

Catalog No. 50-167-4994


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Description

Description

Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity.
Specifications

Specifications

RFXANK
Monoclonal
Unconjugated
RFXANK
Liquid
RFXANK
Full length human recombit protein of human RFXANK produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI3E7
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
O14593
ANKRA1, BLS, F14150_1, RFX-B
Mouse
IgG2b
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
8625
Documents
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