RGS5 Mouse anti-Human, Clone: OTI1E3, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525583
DescriptionRegulators of G protein signaling (RGS proteins) are a family of highly diverse, multifunctional signaling proteins that share a conserved 120 amino acid domain (RGS domain). RGS domains bind directly to activated Galpha subunits and act as GTPase-activating proteins (GAPs) to attenuate and/or modulate hormone and neurotransmitter receptor-initiated signaling by both Galpha-GTP and Gbetagamma. RGS proteins shorten the lifetime of activated G proteins. Vascular endothelial cells express the RGS protein RGS5, where it correlates with capillary morphogenesis, thus rendering it a candidate gene involved in capillary growth, angiogenesis, and also potentially the pathophysiology of stroke.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|RP11-430G6.2, MST092, MST106, MST129, MSTP032, MSTP092, MSTP106, MSTP129|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Western Blot|
|Human recombit protein fragment corresponding to amino acids 1-181 of RGS5 produced in E.coli|
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