Rhotekin Mouse anti-Human, Clone: OTI2E9, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526050
DescriptionThis gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of RTKN produced in HEK293T cell|
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