Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

RIC8A Mouse anti-Human, Clone: OTI3G3, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525075

Catalog No. PIMA525075


Add to cart

Description

Description

Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex. Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.
Specifications

Specifications

RIC8A
Monoclonal
0.83 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q9NPQ8
RIC8A; synembryn; resistance to inhibitors of cholinesterase 8 homolog A (C. elegans); MGC104517; MGC131931; RIC8; RIC8 protein; resistance to inhibitors of cholinesterase 8 homolog A; MGC148073; MGC148074
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
60626
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI3G3
Unconjugated
RIC8A
Liquid
RIC8A
Full length human recombit protein of RIC8A produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit