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RIM1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 245761AP

Catalog No. 50-173-4432


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Description

Description

Rims1 is a RAS gene superfamily member that regulates synaptic vesicle exocytosis. Rims1 also plays a role in the regulation of voltage-gated calcium channels during neurotransmitter and insulin release. Mutations in the Rims1 gene have suggested a role cognition and have been identified as the cause of cone-rod dystrophy type 7. Further, Rims1 may act as scaffold protein that regulates neurotransmitter release at the active zone. Rims1 may also be essential for maintaining normal probability of neurotransmitter release and for regulating release during short-term synaptic plasticity. Rims1 also plays a role in dendrite formation by melanocytes. Multiple transcript variants encoding different isoforms have been described for this Rims1. Diseases associated with RIMS1 include Cone-Rod Dystrophy 7 and Retinitis Pigmentosa.
Specifications

Specifications

RIM1
0.43 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q86UR5, Q99NE5, Q9JIR4
CORD7, KIAA0340, Rab 3 interacting molecule 1, Rab 3 interacting protein 2, RAB3IP2, RIM, RIM 1, RIM1, RIMS1
Rabbit
IgG
150 μL
-20°C
Primary
116837, 22999, 84556
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
RIMS1
Liquid
Rims1
RIM1 Fusion Protein Ag20161
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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