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RIM2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 200931AP

Catalog No. 50-173-2693


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Description

Description

This antibody is specific to RIMS2. It recognizes all the isoforms except isoform7 of RIMS2.

Rab3-interacting molecules (RIMs) are synaptic proteins necessary for neuronal transmission and plasticity. Rim1 and Rim2 proteins are expressed in overlapping but distinct patterns throughout the brain. While the ablation of either gene was not lethal in mice, the deletion of both resulted in postnatal mortality. This lethality is due to a defect in neurotransmitter release; synapses without RIM proteins can still release neurotransmitters but are unable to do so in response to normal Ca2+ triggers. Like Rim1, Rim2 is thought to be an effector protein for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner.
Specifications

Specifications

RIM2
0.28 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q9EQZ7, Q9JIS1, Q9UQ26
KIAA0751, OBOE, Rab 3 interacting molecule 2, Rab 3 interacting protein 3, RAB3IP3, RIM 2, RIM2, RIMS2
Rabbit
IgG
150 μL
-20°C
Primary
116838, 116839, 9699
Western Blot
Unconjugated
RIMS2
Liquid
RIMS2
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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