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  7. RITA, Tocris Bioscience™

RITA, Tocris Bioscience™

Catalog Number 24431
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Quantity:
1 mg
10 mg
This item is not returnable. View return policy
213261-59-7
C14H12O3S2
292.367
KZENBFUSKMWCJF-UHFFFAOYSA-N
rita, rita nsc 652287, p53 activator iii, rita, 5,5'-2,5-furandiyl bis-2-thiophenemethanol, sos bismethanol, rita nsc652287, 5,5'-furan-2,5-diyl bis thiophene-5,2-diyl dimethanol, 2,5-bis-5-hydroxymethyl-2-thienyl-furan, reactivation of p53 and induction of tumor cell apoptosis
374536
[5-[5-[5-(hydroxymethyl)thiophen-2-yl]furan-2-yl]thiophen-2-yl]methanol
C1=C(SC(=C1)C2=CC=C(O2)C3=CC=C(S3)CO)CO
This item is not returnable. View return policy
213261-59-7
C14H12O3S2
292.367
KZENBFUSKMWCJF-UHFFFAOYSA-N
rita, rita nsc 652287, p53 activator iii, rita, 5,5'-2,5-furandiyl bis-2-thiophenemethanol, sos bismethanol, rita nsc652287, 5,5'-furan-2,5-diyl bis thiophene-5,2-diyl dimethanol, 2,5-bis-5-hydroxymethyl-2-thienyl-furan, reactivation of p53 and induction of tumor cell apoptosis
374536
[5-[5-[5-(hydroxymethyl)thiophen-2-yl]furan-2-yl]thiophen-2-yl]methanol
C1=C(SC(=C1)C2=CC=C(O2)C3=CC=C(S3)CO)CO

Description

MDM2-p53 interaction inhibitor

Anti-tumor agent that binds wild-type p53 (Kd = 1.5 nM) preventing p53-MDM2 (HDM2) interaction. Induces p53 accumulation and stimulates apoptosis in tumor cell lines expressing wild-type p53 in vitro and in vivo. Inhibits HPV-E6-mediated proteasomal degradation. Suppresses expression of cervical carcinoma HeLa xenografts in vivo.
Quantity 1 mg
Formula Weight 292.37
Percent Purity >97%
Chemical Name or Material RITA

Safety and Handling

Recommended Storage Store at -20°C
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