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RNF14 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550873

Catalog No. PA550873


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Description

Description

The antibody detects endogenous levels of total RNF14 protein.

The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A domit negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.
Specifications

Specifications

RNF14
Polyclonal
Unconjugated
RNF14
Liquid
RNF14
Fusion protein corresponding to residues near the N terminal of human ring finger protein 14
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin), Western Blot
1.2 mg/mL
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Q9UBS8, Q9JI90
ARA54
Rabbit
IgG
100 μL
-20°C
Primary
56736, 9604
Documents
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