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RNF41 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 172331AP

Catalog No. 50-173-1456


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Description

Description

The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. Nrdp1, also known as RNF41 (RING finger protein 41), SBBI03 or FLRF, is a 317 amino acid protein that contains one RING-type zinc finger and one SIAH-type zinc finger. Expressed in testis, ovary and prostate, Nrdp1 functions as an E3 ubiquitin-protein ligase that, characteristic of E3 ligase proteins, accepts ubiquitin (in the form of a thioester) from an E2 ubiquitin-conjugating enzyme and transfers that ubiquitin residue to substrates targeted for degradation. Specifically, Nrdp1 interacts with ErbB-3 and UBPY, thereby targeting them for proteasomal degradation.
Specifications

Specifications

RNF41
0.29 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q8BH75, Q9H4P4
FLRF, NRDP1, ring finger protein 41, RNF41, SBBI03
Rabbit
IgG
150 μL
-20°C
Primary
10193, 362814, 67588
Western Blot
Unconjugated
RNF41
Liquid
Rnf41
RNF41 Fusion Protein Ag11076
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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