Tocris™ Ro 48-8071 fumarate

2,3-Oxidosqualene cyclase (OSC) inhibitor

Manufacturer: Tocris™ 5389/50

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Catalog No. 53-895-0

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For Research Use Only


    Specifications

    Product Type Ro 48-8071 fumarate
    Inhibitors Ro 48-8071 fumarate
    Purity >99
    Molecular Weight 564.44
    Quantity 50mg

    2,3-Oxidosqualene cyclase (OSC) inhibitor (IC50 = 6.5nM); blocks cholesterol synthesis in HepG2 cells. Reduces viability of breast cancer cell lines. Also inhibits Ebola virus (EBOV) cell entry (IC50 = 1.74µM).

    • Chemical Name: (4-Bromophenyl)[2-fluoro-4-[[6-(methyl-2-propen-1-ylamino)hexyl]oxy]phenyl]methanone
    • Formula: C23H27BrFNO2.C4H4O4
    • CAS Number: 189197-69-1
    • Solubility: Soluble to 20mM in water with gentle warming and to 100mM in DMSO
    • Purity: >99

  • Description & Specifications

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