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Tocris™ Ro 48-8071 fumarate

2,3-Oxidosqualene cyclase (OSC) inhibitor

Manufacturer:  Tocris™ 5389/10

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Catalog No. 53-891-0

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For Research Use Only



2,3-Oxidosqualene cyclase (OSC) inhibitor (IC50 = 6.5nM); blocks cholesterol synthesis in HepG2 cells. Reduces viability of breast cancer cell lines. Also inhibits Ebola virus (EBOV) cell entry (IC50 = 1.74µM).
  • Chemical Name: (4-Bromophenyl)[2-fluoro-4-[[6-(methyl-2-propen-1-ylamino)hexyl]oxy]phenyl]methanone
  • Formula: C23H27BrFNO2.C4H4O4
  • CAS Number: 189197-69-1
  • Solubility: Soluble to 20mM in water with gentle warming and to 100mM in DMSO
  • Purity: >99
Description & Specifications


Ro 48-8071 fumarate
Ro 48-8071 fumarate
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