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Thermo Scientific™ Lab Vision™ ROC1 Ab-1, Rabbit Polyclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ ROC1 Ab-1, Rabbit Polyclonal Antibody.

$202.00 - $1022.00

Specifications

Antigen ROC1 Ab-1
Concentration 1mg/mL
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 5
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
RB069P
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Thermo Scientific™
RB069P
Purified Ab with BSA and Azide 1mL Each for $947.00
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RB069P0
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Thermo Scientific™
RB069P0
Purified Ab with BSA and Azide 100μL Each for $202.00
Add to cart
 
RB069P1
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Thermo Scientific™
RB069P1
Purified Ab with BSA and Azide 500μL Each for $573.00
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RB069P1ABX
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Thermo Scientific™
RB069P1ABX
Ab without BSA/Azide (Frozen) 500μL Each for $626.00
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RB069PABX
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Thermo Scientific™
RB069PABX
Ab without BSA/Azide (Frozen) 1mL Each for $1,022.00
Add to cart
 
Description

Description

Provide accurate, reproducible results with the Thermo Scientific™ ROC1 Ab-1, Rabbit Polyclonal Antibody.

ROC1 and ROC2 are the two highly conserved RING finger proteins that are homologous to APC11, a subunit of the anaphase-promoting complex(APC). ROC1 and ROC2 commonly interact with all cullins while APC11 specifically interacts with APC2, a cullin-related APC subunit. ROC1 and APC11 immunocomplexes can catalyze isopeptide ligations to form polyubiquitin chains in an E1- and E2-dependent manner. ROC1 is thought to play a unique role in the ubiquitination reaction by heterodimerizing with cullin1 to catalyze ubiquitin polymerization.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human and Mouse. Others not known.

Epitope: aa 97-108

Immunogen: A peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1

Molecular Weight: 13kDa

Positive Control: HeLa cells

Cellular Localization: Nuclear

Recommended for:

  • Western Blotting
  • Immunoprecipitation (Native verified)
General References:

1. Tan P, et al. Mol Cell 1999 Apr 3 (4): 527.

2. Skowyra D, et al. Science 1999. 284 (5414): 662.

3. Ohta T, et al. Mol Cell 1999 Apr 3(4): 535.

Specifications

Specifications

ROC1 Ab-1
Western Blot
Unconjugated
Rabbit
Cell Cycle
A peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1
1mg/mL
Polyclonal
Concentrated
RUO
Primary
IgG
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