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Thermo Scientific™ Lab Vision™ ROC1 Ab-1, Rabbit Polyclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ ROC1 Ab-1, Rabbit Polyclonal Antibody.

Manufacturer:  Thermo Scientific™ RB069PABX

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Catalog No. RB069PABX


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Description

Description

Provide accurate, reproducible results with the Thermo Scientific™ ROC1 Ab-1, Rabbit Polyclonal Antibody.

ROC1 and ROC2 are the two highly conserved RING finger proteins that are homologous to APC11, a subunit of the anaphase-promoting complex(APC). ROC1 and ROC2 commonly interact with all cullins while APC11 specifically interacts with APC2, a cullin-related APC subunit. ROC1 and APC11 immunocomplexes can catalyze isopeptide ligations to form polyubiquitin chains in an E1- and E2-dependent manner. ROC1 is thought to play a unique role in the ubiquitination reaction by heterodimerizing with cullin1 to catalyze ubiquitin polymerization.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human and Mouse. Others not known.

Epitope: aa 97-108

Immunogen: A peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1

Molecular Weight: 13kDa

Positive Control: HeLa cells

Cellular Localization: Nuclear

Recommended for:

  • Western Blotting
  • Immunoprecipitation (Native verified)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

ROC1 Ab-1
Polyclonal
Unconjugated
Concentrated
A peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1
1mL
Cell Cycle
Primary
Human
Western Blot
1mg/mL
Ab without BSA/Azide (Frozen)
Rabbit
IgG
RUO
Primary
Polyclonal
SDS
Documents
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