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ROS1 Mouse anti-Human, Clone: OTI1A1, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526760

Catalog No. PIMA526760


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Description

Description

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
Specifications

Specifications

ROS1
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
P08922
Proto-oncogene tyrosine-protein kinase ROS; c-ros-1; ROS1
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
6098
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI1A1
Unconjugated
ROS1
Liquid
ROS1
Human recombit protein fragment corresponding to amino acids 1882-2125 of ROS1 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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