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RPS6KB1 Mouse anti-Canine, Human, Mouse, Clone: OTI6B2, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA502929

Catalog No. 50-167-3924


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Description

Description

The p70 S6 kinase (p70 Ribosomal Protein S6 Kinase, p70S6K) is a 70 kDa member of the ribosomal S6 kinase (RSK) family of serine/threonine kinases. p70 S6 kinase is predomitly localized in the cytoplasm, and is essential in growth factors regulated cell proliferation, pathways involving cell motility, such as metastases, the immune response, and tissue repair. p70 S6 kinase acts downstream of phosphoinositide (PI) 3-kinase, and its main physiological target is the S6 ribosomal protein, which is involved in upregulation of protein synthesis. The kinase activity of p70 S6 kinase leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding p70 S6 kinase and overexpression are seen in some breast cancer cell lines.
Specifications

Specifications

RPS6KB1
Monoclonal
0.7 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P23443, Q8BSK8
PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
480580, 6198, 72508
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI6B2
Unconjugated
RPS6KB1
Liquid
RPS6KB1
Full length human recombit protein of human RPS6KB1 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Canine, Human, Mouse
Documents
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