Invitrogen™ RRAD Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA537885

Catalog No. PIPA537885

Description

This antibody is predicted to react with human, rat, dog, pig and cow based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.

The Ras-encoded family of proteins bind GDP and GTP with high affinity. They possess a low level of intrinsic GTPase activity that increases more than 100-fold when interacting with cytosolic GTPase activating protein (GAP). Ras family members include H-Ras, K-Ras, N-Ras, M-Ras, R-Ras, ERas, Rheb, TC 21, RASL11B and Rad (Ras associated with diabetes) GTPase.Rad GTPase is a GTP-binding protein that is similar to Ras but has unique features. Unlike other small GTPases, Rad GTPase lacks typical pren-ylation motifs at its C terminus. The Rad GTPase enzyme binds calmodulin, inhibits vascular lesion formation, has low intrinsic GTPase activity and cannot be stimulated by any known GAP molecules. Rad GTPase is expressed in skeletal muscle, cardiac muscle and lung tissues and is overexpressed in the skeletal muscle tissue of individuals with type II diabetes.

Specifications

• Antigen: RRAD
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RRAD
• Gene Alias: GTP-binding protein RAD; RAD; RAD1; RAS (RAD and GEM) like GTP binding 3; ras associated with diabetes; Ras-like GTP-binding protein rad; Ras-related associated with diabetes; REM3; RRAD; RRAD, Ras related glycolysis inhibitor and calcium channel regulator; RRAD, Ras related glycolysis inihibitor and calcium channel regulator
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 56437
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O88667
• Gene Symbols: RRAD
• Immunogen: Peptide with sequence C-HRRSMPVDERDLQ, from the internal region of RRAD (aa36-48).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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