RRM1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 196861AP
The antibody is specific to RRM1.This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in maligcies and disease that involve this region.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|R1, ribonucleotide reductase M1, RIR1, RR1, RRM1|
|20133, 6240, 685579|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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