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RRM1 Mouse anti-Human, Clone: OTI5G5, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526497

Catalog No. PIMA526497


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Description

Description

This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in maligcies and disease that involve this region.
Specifications

Specifications

RRM1
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
P23921
R1; Ribonucleoside diphosphate reductase large subunit; Ribonucleoside diphosphate reductase M1 chain; Ribonucleoside diphosphate reductase subunit M1; Ribonucleoside-diphosphate reductase large subunit; Ribonucleoside-diphosphate reductase subunit M1; Ribonucleotide reductase large chain; Ribonucleotide reductase large subunit; Ribonucleotide reductase M1; Ribonucleotide reductase M1 polypeptide; Ribonucleotide reductase R1 subunit; RIR 1; RIR1; RIR1; RR 1; RR1; RRM 1; RRM1;
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
6240
Immunohistochemistry (Paraffin), Western Blot
OTI5G5
Unconjugated
RRM1
Liquid
RRM1
Human recombit protein fragment corresponding to amino acids 541-792 of RRM1 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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