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  6. RSVA 405, Tocris Bioscience™

RSVA 405, Tocris Bioscience™

Catalog Number p-4835960
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
140405-36-3
C17H20N4O2
312.373
FTNOOTQIBBIZHI-UHFFFAOYSA-N
rsva 405, n'-1e-4-diethylamino-2-hydroxyphenyl methylidene pyridine-4-carbohydrazide, n'-4-diethylamino-2-hydroxybenzylidene isonicotinohydrazide, e-n'-4-diethylamino-2-hydroxybenzylidene isonicotinohydrazide, n'-2-hydroxy-4-diethylamino benzylidene pyridine-4-carbohydrazide, n'-4-diethylamino-6-oxocyclohexa-2,4-dien-1-ylidene methyl pyridine-4-carbohydrazide, n'-4-diethylamino-2-hydroxyphenyl methylidene pyridine-4-carbohydrazide
6739376
N'-[[4-(diethylamino)-6-oxocyclohexa-2,4-dien-1-ylidene]methyl]pyridine-4-carbohydrazide
CCN(CC)C1=CC(=O)C(=CNNC(=O)C2=CC=NC=C2)C=C1
This item is not returnable. View return policy
140405-36-3
C17H20N4O2
312.373
FTNOOTQIBBIZHI-UHFFFAOYSA-N
rsva 405, n'-1e-4-diethylamino-2-hydroxyphenyl methylidene pyridine-4-carbohydrazide, n'-4-diethylamino-2-hydroxybenzylidene isonicotinohydrazide, e-n'-4-diethylamino-2-hydroxybenzylidene isonicotinohydrazide, n'-2-hydroxy-4-diethylamino benzylidene pyridine-4-carbohydrazide, n'-4-diethylamino-6-oxocyclohexa-2,4-dien-1-ylidene methyl pyridine-4-carbohydrazide, n'-4-diethylamino-2-hydroxyphenyl methylidene pyridine-4-carbohydrazide
6739376
N'-[[4-(diethylamino)-6-oxocyclohexa-2,4-dien-1-ylidene]methyl]pyridine-4-carbohydrazide
CCN(CC)C1=CC(=O)C(=CNNC(=O)C2=CC=NC=C2)C=C1

Description

AMPK activator; also STAT3 inhibitor

AMP-activated protein kinase (AMPK) activator (EC50 = 1 μM); activates AMPK indirectly through a CaMKKβ-dependent mechanism. Also inhibits LPS-induced STAT3 phosphorylation (IC50 = 0.5 μM). Induces autophagy and promotes Aβ degradation in vitro. Also inhibits adipogenesis in vitro and reduces weight gain in diet-induced obese mice.
Quantity 10 mg
Formula Weight 312.37
Chemical Name or Material RSVA 405

Safety and Handling

Recommended Storage Store at -20°C
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