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Alfa Aesar™ (S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid, 99%

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Quantity:
500mg
2.5g
17257-71-5
C10H9F3O3
234.174
MFCD00064200
JJYKJUXBWFATTE-VIFPVBQESA-N
s---alpha-methoxy-alpha-trifluoromethyl phenylacetic acid,s-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid,--mosher's acid,--mtpa,unii-172hcj1iqv,172hcj1iqv,2s-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid,--alpha-methoxy-alpha-trifluoromethyl phenylacetic acid,s---mtpa,--a-methoxy-a-trifluoromethylphenylacetic acid
6992788
(2S)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid
COC(C1=CC=CC=C1)(C(=O)O)C(F)(F)F
17257-71-5
C10H9F3O3
234.174
MFCD00064200
JJYKJUXBWFATTE-VIFPVBQESA-N
s---alpha-methoxy-alpha-trifluoromethyl phenylacetic acid,s-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid,--mosher's acid,--mtpa,unii-172hcj1iqv,172hcj1iqv,2s-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid,--alpha-methoxy-alpha-trifluoromethyl phenylacetic acid,s---mtpa,--a-methoxy-a-trifluoromethylphenylacetic acid
6992788
(2S)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid
COC(C1=CC=CC=C1)(C(=O)O)C(F)(F)F
Applications
(S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid is used as a chiral derivatizing agent, it reacts with an alcohol or amine of unknown stereochemistry to form an ester or amide. The absolute configuration of the ester or amide is then determined by proton and/or 19F NMR spectroscopy.

Solubility
Readily soluble in hexane, ether, THF, CH2Cl2, benzene.

Notes
Hygroscopic. Store under inert gas. Store away from oxidizing agents, moisture.
Melting Point 43°C to 45°C
Optical Rotation −72° (c=2 in Methanol)
Boiling Point 105°C to 107°C (1mmHg)
Quantity 500mg
Flash Point >110°C (230°F)
Beilstein 3591561
Merck Index 14,6280
Formula Weight 234.18
Percent Purity 99%
Chemical Name or Material (S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

Recommended Storage : 2° to 8°C