S100B Mouse anti-Human, Clone: 9A11B9, Abnova™
Mouse monoclonal antibody raised against human S100B.
Manufacturer: Abnova Corporation MAB12577
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq]
|Mouse monoclonal antibody raised against human S100B.|
|In ascites (0.03% sodium azide).|
|ELISA, Immunohistochemistry (PFA fixed), Western Blot|
|ELISA (1:10000) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.|
|Recombinant protein corresponding to human S100B.|
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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