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S100B Mouse anti-Human, Mouse, Rat, Bovine, PE/Cy5.5, Clone: S100B/1012, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP259619PECY55

Catalog No. N259619PEC5


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Description

Description

S100B Monoclonal antibody specifically detects S100B in Human, Mouse, Rat, Bovine samples. It is validated for Flow Cytometry.
Specifications

Specifications

S100B
S100B/1012
Flow Cytometry
Conjugated, Purified
S100B
Recombinant full-length human S100B protein
Protein A or G purified
Apoptosis, Biologically Active Proteins, Cytoskeleton Markers, Neuroscience, Signal Transduction, Stem Cells
Primary
6285.0
Bovine, Human, Mouse, Rat
Flow Cytometry
PE-Cyanine5.5
PBS with 0.05% Sodium Azide
beta (neural), NEF, S100, S100 beta, S100 calcium binding protein B, S100 calcium-binding protein B, S100 calcium-binding protein, beta (neural), S-100 calcium-binding protein, beta chain, 10protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100beta
Mouse
IgG2a Kappa
0.1 mL
Store at 4°C in the dark. Do not freeze.
Monoclonal
The specificity of this monoclonal antibody to S100B was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta -chain (i.e. in S-100A and S-100B) but not on the alpha-chain of S-100 (i.e. in S-100A and S100A0). This antibody can be used to localize S-100A and S-100B in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lip ocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell -derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S -100 protein
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