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S1P1 Mouse anti-Human, Clone: 2B9, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA528123

Catalog No. PIMA528123


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Description

Description

S1P1 is a G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that is coupled to the G(i) subclass of heteromeric G proteins. S1P1 signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. It plays an important role in cell migration via its role in the reorganization of the actin cytoskeleton and formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. S1P1 is required for normal chemotaxis toward sphingosine 1-phosphate, normal embryonic heart development, and normal cardiac morphogenesis.
Specifications

Specifications

S1P1
Monoclonal
1 mg/mL
PBS with 0.09% sodium azide
P21453
S1PR1
IgG2a
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
1901
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
2B9
Unconjugated
S1PR1
Liquid
Mouse
Protein A
RUO
Antibody
Monoclonal
Human
Documents
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