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SAFB Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 218571AP

Catalog No. 50-173-3611


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Description

Description

This antibody specifically reacts with the isoform 1 of human SAFB protein. SF3A1, also known as SF3a120, is a 793 amino acid protein, which is a Subunit of the splicing factor SF3A required for  ft.A ft. complex assembly formed by the stable bindin

This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a  ft.transcriptosome complex ft. in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

SAFB
0.17 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q15424
HAP, HET, HSP27 ERE TATA binding protein, SAF B, SAF B1, SAFB, SAFB1, scaffold attachment factor B, Scaffold attachment factor B1
Rabbit
IgG
150 μL
-20°C
Primary
6294
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
SAFB
Liquid
SAFB
SAFB Fusion Protein Ag16451
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
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