SAFB1, Polyclonal, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Bethyl Laboratories, Inc A300811AT
The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predictThis gene encodes a DNA-binding protein that has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. This encoded protein is thought to serve as a molecular base to assemble a ′transcriptosome complex′ in the vicinity of actively transcribed genes. It is involved in the regulation of the heat shock protein 27 transcription and also can act as an estrogen receptor corepressor. This gene is a candidate gene for breast tumorigenesis.
|TBS with 0.1% BSA and 0.09% sodium azide|
|DKFZp779C1727, HAP, HET, SAFB1|
|Immunohistochemistry, Western Blot|
|Between 775 and 825|
|Antigen affinity chromatography|
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