Tocris™ Salirasib

Ras inhibitor; also induces autophagy

Manufacturer: Tocris™ 4989/10

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Catalog No. 49-891-0R

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For Research Use Only


    Product Type Salirasib
    Inhibitors Salirasib
    Purity >98
    Molecular Weight 358.54
    Quantity 10mg

    Inhibitor of active Ras proteins. Displaces active Ras from the plasma membrane; impairs downstream signaling and inhibits proliferation of endometrial carcinoma cells. Also facilitates Ras degradation. Shown to induce autophagy in several human cancer cell lines.

    • Chemical Name: 2-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl]thio]benzoic acid
    • Formula: C22H30O2S
    • CAS Number: 162520-00-5
    • Solubility: Soluble to 100mM in DMSO and to 50mM in 1eq. NaOH
    • Purity: >98

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