Ras inhibitor; also induces autophagy
Manufacturer: Tocris 4989/50
DescriptionInhibitor of active Ras proteins. Displaces active Ras from the plasma membrane; impairs downstream signaling and inhibits proliferation of endometrial carcinoma cells. Also facilitates Ras degradation. Shown to induce autophagy in several human cancer cell lines.
- Chemical Name: 2-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl]thio]benzoic acid
- Formula: C22H30O2S
- CAS Number: 162520-00-5
- Solubility: Soluble to 100mM in DMSO and to 50mM in 1eq. NaOH
- Purity: >98
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