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Sanguinarine chloride

Inhibitor of protein phosphatase 2C (PP2C)

Supplier:  R&D Systems 2302/25

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Catalog No. 23-022-5


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Description

Description

Sanguinarine chloride is an inhibitor of protein phosphatase 2C (PP2C), selective over PP1, PP2A and PP2B in vitro. Also inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) (IC50 = 10 μM). Plant alkaloid that exhibits anti-inflammatory and antioxidant activity. Blocks cell cycle in the G1 phase; inhibits cell growth in human prostate carcinoma cells.
Specifications

Specifications

13-Methyl-[1,3]-benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium chloride
>97%
C20H14ClNO4
5578-73-4
25 mg
Observed MW: 367.78
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Safety and Handling

Safety and Handling

Recommended Storage : Store at 4°C

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