Tocris™ SANT-2

Inhibitor of Hedgehog (Hh) signaling; antagonizes smoothened activity

Manufacturer: Tocris™ 3617/10

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Catalog No. 36-171-0R

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For Research Use Only


    Inhibitors SANT-2
    Purity >98
    Molecular Weight 479.96
    Quantity 10mg
    Product Type SANT-2

    Inhibitor of Sonic hedgehog (Shh) signaling; antagonizes smoothened receptor activity (KD = 12nM). Displays allosteric binding characteristics similar to SANT-1 (Cat. No. 1974). Displaces smo-[3H]SAG-1.3 and -[3H]Cyclopamine binding (Ki values are 7.8nM and 8.4nM respectively).

    • Chemical Name: N-[3-(1H-Benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide
    • Formula: C26H26ClN3O4
    • CAS Number: 329196-48-7
    • Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
    • Purity: >98

  • Description & Specifications

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