SAP18 Mouse anti-Human, Clone: 3B2, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524433
Peptide Sequence: MAVESRVTQE EIKKEPEKPI DREKTCPLLL RVFTTNNGRH HRMDEFSRGN VPSSELQIYT WMDATLKELT SLVKEVYPEA RKKGTHFNFA IVFTDVKRPG YRVKEIGSTM SGRKGTDDSM TLQSQKFQIG DYLDIAITPP NRAPPTSGRM RPYHistone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.
|SAP18 (AAH30836, 1 a.a. ∽ 153 a.a) full-length recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
|ELISA, Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with no preservative; pH 7.4|
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