SAP30BP Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 209431AP150UL

Catalog No. 50-173-3166

Description

Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.

Specifications

• Antigen: SAP30BP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SAP30BP
• Gene Alias: HCNGP, HTRG, HTRP, SAP30 binding protein, SAP30BP
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29115, 57230
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.47 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q02614, Q9UHR5
• Gene Symbols: SAP30BP
• Immunogen: SAP30BP Fusion Protein Ag15051
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG