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SAP30BP Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 209431AP

Catalog No. 50-173-3166


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Description

Description

Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.
Specifications

Specifications

SAP30BP
0.47 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q02614, Q9UHR5
HCNGP, HTRG, HTRP, SAP30 binding protein, SAP30BP
Rabbit
IgG
150 μL
-20°C
Primary
29115, 57230
Western Blot
Unconjugated
SAP30BP
Liquid
SAP30BP
SAP30BP Fusion Protein Ag15051
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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