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SART1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 226751AP

Catalog No. 50-173-3920


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Description

Description

This antibody recognizes the endogenous 800-amino acid SART1, which migrates with an apparent molecular mass of 110 kDa in SDS-PAGE.

This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.
Specifications

Specifications

SART1
0.33 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O43290, Q9Z315
Ara1, Hom s 1, HOMS1, hSART 1, hSnu66, SART 1, SART1, SART1259, SNRNP110, Snu66, SNU66 homolog
Rabbit
IgG
150 μL
-20°C
Primary
20227, 9092
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Unconjugated
SART1
Liquid
SART1
SART1 Fusion Protein Ag18478
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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