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SASS6 Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 213771AP

Catalog No. 50-173-3394


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Description

Description

Metadherin (Metastasis adhesion protein), also known as MTDH, LYsine-RIch CEACAM1 co-isolated (LYRIC), is a novel protein that localizes with the tight junction proteins ZO-1 and occludin in polarized epithelial cells. At the tight junction, it acts not as a structural component, but is rather recruited during the maturation of the tight junction complex. Metadherin is overexpressed in breast cancer tissue and breast tumor xenografts, while much lower levels are expressed in normal breast tissue. Metadherin binds to lung vasculature, one of the four common sites of breast cancer metastasis, through a C-terminal segment in the extracellular domain; blocking this lung-homing domain with antibodies or inhibiting metadherin with siRNA has been reported to inhibit breast cancer metastasis.
Specifications

Specifications

SASS6
0.42 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q6UVJ0
HsSAS 6, SAS 6, SAS6, SASS6
Rabbit
IgG
150 μL
-20°C
Primary
163786
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
SASS6
Liquid
SASS6
SASS6 Fusion Protein Ag15917
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Documents
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